Anti-inflammatory activity of Ficus carica and Ziziphus spina-christi leaves
Muhammad Fariez Kurniawan; Muh Indra Irawan; Ariffadli Prakoso; Nining Sugihartini

School of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta

Faculty of Pharmacy, Universitas Ahmad Dahlan

Abstract

Medicine (TCM) because of the Ying (cold) element they have; This study aims to know the influence of various concentration ethanolic extract of Ficus carica and Ziziphus spina-christi leaves on cream and gel formulation to anti-inflammatory activity; This study used fifteen treatment groups; each of which consisted of six mice with balb / c strains; Fifteen groups included three control groups namely one group that received base cream and gel without extract; one group that became a positive control by giving voltaren emulgel; and one group that was induced by croton oil without healing; The other 12 groups were inflammatory-induced groups with croton oil and received tin extract cream and bidara leaves; The results of study showed the increasing concentration of ethanolic extract of FC and ZS leaves caused the decreasing of the value of COX-2; thickness of epidermis and the amount of inflammatory cell; The gel has the best antiinflammatory effect compared to cream;

Keywords: Ficus carica; Ziziphus spina-christi; Antiinflamation

Topic: International Symposium of Engineering, Technology, and Health Sciences

Link: https://ifory.id/abstract-plain/GLN28PMm7CbB

Web Format | Corresponding Author (Muhammad Fariez Kurniawan)