Superoxide Dismutase and Malondialdehyde Levels in Adolescents with Primary Dysmenorrhea
Mukhoirotin Mukhoirotin, Kurniawati, Diah Ayu Fatmawati
Nursing Science Program, Faculty of Health Science, Unipdu Jombang, Indonesia
Abstract
Primary dysmenorrhoea is painful menstruation without pelvic abnormalities and usually occurs among adolescents and female adults. In primary dysmenorrhea occurred the increasing of lipid peroxide (oxidative stress) and decreasing of antioxidant level. The aim of this study was to identified the differences of Superokside Dismutase and Malondialdehyde levels in adolescents with primary dysmenorrhoea. The research design used Case Control. The population of this study was all female students at Faculty of Health Sciences Unipdu Jombang who got menstruation, the sample of this study were 24 respondents who met the inclusion and exclusion criteria. Sampling method in this study used Purposive Sampling technique. To measuring SOD levels used the NBT method, MDA levels used the Thiobarbituric Acid (TBA) test, and the measurement were used Spektrofotometer. The data were analyzed by using Independent Sample T-Test with α ≤ 0.05. Independent Sample T-Test results showed that there were significant differences between SOD and MDA levels in both of case group and control group (p <0.05). In primary dysmenorrea there is an increasing of Malondialdehyde (MDA) levels and a decrease in superoxide dismutase (SOD) levels, so the requiring efforts to balance the condition and reduce symptoms of primary dysmenorrhoea are needed.
Keywords: Malondialdehid, Superoxide dismutase, Dismenorrea primer
Topic: Health Science