Molecularly Imprinted Polymer as a Sorbent for Alpha Mangostin
Neena Zakia (a,b*), Handajaya Rusli (a), M. Ali Zulfikar (a), M. Bachri Amran (a)
a) Division of Analytical Chemistry, Institut Teknologi Bandung
Jalan Ganesha 10, Bandung 40132, Indonesia
*neena.zakia.fmipa[at]um.ac.id
b) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang
Jalan Semarang 5, Malang 65145, Indonesia
Abstract
Alpha mangostin is a major component in the mangosteen rind, which has activity as an antioxidant, antitumor, hypo-allergenic, and anticancer. The aim of this study is to synthesize molecularly imprinted polymer (MIP) for alpha mangostin adsorption. The MIP was prepared by bulk polymerization with alpha mangostin as template, methacrylic acid as the monomer, ethylene glycol dimethacrylate as the crosslinker, and benzoyl peroxide as the initiator and acetonitrile as porogenic solvent. A molar ratio of template:monomer:crosslinker is 5:4:20. A non-imprinted polymer was synthesized in the absence of alpha mangostin. Solvent extraction is carried out to remove the template used methanol:acetic acid (90:10, %v/v) as the solvent. The surface morphology of MIP was visualized by scanning electron microscopy (SEM). The synthesized MIP was characterized by infra red spectroscopy. It showed that wavelength number were 2957, 1603, and 1456 cm-1 assigned to characteristic vibration of a C-H bond, a chelated carbonyl group and a methoxy groups, respectively, which indicated the present of template molecule. The adsorption capacity of MIP for alpha mangostin was 12,17 mg/g with the imprinting factor 1,2. Overall, this MIP has a good chance to be used as functional material for alpha mangostin adsorption.
Keywords: alpha mangostin, molecularly imprinted polymer, adsorption
Topic: Chemistry