The long duration of electrical stimulation impairs wound healing process
Yunita Sari1, Eman Sutrisna2, Hartono3
1Department of nursing science, Universitas Jenderal Soedirman, Indonesia
2. Department of medical science, Universitas Jenderal Soedirman, Indonesia
3. Department of Physics, Universitas Jenderal Soedirman, Indonesia
Corresponding Author: Yunita Sari (sasa.yunita[at]gmail.com)
Abstract
Background : Electrical stimulation (ES) has been known to have beneficial effect in improving wound healing. Previous studies showed that short duration of application of EST could lower inflammation, improve collagen desposition, improve VEGF positive cells. In order to investigate the safety of the use of EST, it is needed to assess the effect of long duration of application of EST (LD-EST) on tissue damage during wound healing process. The purpose of this study was to investigate the effect of long duration of application of EST on tissue damage during wound healing process. Method : The wound was created in the back side of the rat. The rats were divided into two groups, long duration application of EST group (LD-EST group) and control group. The wound bed appearance, necrotic tissue, inflammation, collagen desposition, were compared between two groups. Result : On day 8 to 9, wound size was significantly bigger in the LD-EST group compared with control group. The size of the necrotic tissue was larger in the LD-EST group compared with control group. The intensity of the inflammation was also significantly higher in the the LD-EST group compared with control group. Reepithelialization was longer in the control group than in the LD-EST group. Conclusion: Long duration of application of EST will cause more tissue necrotic, and higher inflammation to the wound tissue. In addition, the long duration of application of EST also cause longer time of reepithelialization. Therefore, it is not recommended to apply EST for long duration to avoid the tissue damage.
Keywords: electrical stimulation, tissue, damage
Topic: Nursing