The Effect of Adding Aloe Vera Gel Extract to The Burn Cream Formulation
Novianti Universitas Muhammmadiyah Jakarta, novianti2302@gmail.com, Tri Yuni Hendrawati Universitas Muhammmadiyah Jakarta, Jakarta, yuni.hendrawati@ftumj.ac.id, Ratri Ariatmi Nurgahani Universitas Muhammmadiyah Jakarta, Jakarta, ratriariatmi@gmail.co
Universitas Muhammadiyah Jakarta, fakultas teknik, jurusan Teknik Kimia
Abstract
Aloe vera gel contains various anti inflammatory substances salicylic acid, indomethacin, manosa 6 phosphate, B sitosterol, lignin, saponins and anthaquinone. The purpose of this study was to obtain the effect of adding Aloe vera gel extract to burn cream and obtain the best formulation in healing burns on the skin of the outer epidermis by testing in white mice. Aloe vera gel was extracted using an vacuum rotary evaporator for 90 minutes, at 40 degree C at a pressure of 110 mBar. Burns cream made with 7 different formulas, namely Aloe vera extract, stearate acid, propylene glycol, liquid paraffin and Tween 80 and nipagin, nipasol, EDTA, Dimethyl sulfur oxide, NaH2PO4, Trietanolamine with the addition of Aloe vera extract 0%, 2.5%, 5%, 7.5%, 10% and 12.5%. In testing pH meets skin physiological pH requirement 4 to 8. Viscosity with a consistency of cream that is easily applied to the skin without dripping. Fineness 9 to 11, refractive index 1.1 In the Aloe vera gel extract and on the cream base ranged from 51.5 to 78.3. In the results of testing with white mice, the best formula was obtained by adding 5percent Aloe vera gel extract with healing of burns for 7 days.
Keywords: Aloe Chinensis Baker, cream extract, burns, skin epidermis
Topic: International Symposium of Engineering, Technology, and Health Sciences