GHRELIN PROTEIN PLANT ORIGIN AS A MATERIAL FOR REGULATION OF ENERGY BALANCE FOR FEED EFFICIENCY
Nove Hidajati (a*) Ratna Damayanti (a) Chairul Anwar (b)
(a) Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga Surabaya
(b) Department of Anatomi Veterinary, Faculty of Veterinary Medicine, Universitas Airlangga Surabaya
Abstract
Ghrelin is a gastric peptide that plays an important role in regulating food that enters the body (food intake). Before eating plasma ghrelin concentration rises gradually and immediately drops after eating. Addition of ghrelin intravenously increases food intake and triggers appetite (appetite), this proves that ghrelin plays a role in hunger and the initial desire to eat (meal initiation). Ghrelin was also involved in weight control because the body mass index was negatively controlled by plasma ghrelin concentration at fasting time. Signal abnormalities originating from the stomach will be related to energy balance disorders, growth and this is related to gastrointestinal and neuroendocrine function. Knowledge that shows between the relationship of ghrelin, ghrelin receptors, hypothalamus and the implications of ghrelin in controlling gastrointestinal function, energy balance, current growth is still not entirely clear. In previous studies it was known that in broiler chickens the molecular weight of ghrelin protein is 13.4 kDa and the amino acid composition of the ghrelin protein is mflrvil or methionine, phenylalanine, leucine, arginine, valine, isoleucine, leucine. The results showed that the exploration of natural ingredients came from Ipomoea aquaticum, Nasturtium officinale, Manihot esculena showed the presence of ghrelin protein. Ghrelin results from plants are then used for experiments in several experimental animals. With the discovery of ghrelin protein from natural ingredients from plants, it can be used to regulate energy balance so that there is an increase in feed efficiency.
Keywords: Ghrelin, Plant Ghrelin, Energy Balance, Efficiency Feed
Topic: Health and Medicine