PENGUJIAN EKSTRAK BONGGOL PISANG TERHADAP KADAR GULA DARAH PADA TIKUS YANG DIINDUKSI ALOKSAN
Desy Muliana Wenas(a), Lisana Sidqi Aliya(a), Ika Septiana (a)
(a) Laboratorium Farmakologi, Fakultas Farmasi, Insititut Sains dan Teknologi Nasional, Jakarta
Abstract
Some part of banana could be used for traditional medicine. The corm of banana contains more potential phytochemical than the stem sap or the fruit skin. Therefore, the corm of banana is being studied. The aim of this research is to determine the effect of Banana Corm Extract (KBCE) on aloxan-induced rat. The banana corm was being dried, powdered and extracted using 70% ethanol by maceration method for 24 hours for 3 times. Extract with concentration of 10%, 15%, 20%, glibenclamide as positive control, CMC-Na as negative control are prepared. Six groups of 4 male wistar rats, were wounded and given the treatment respectively 5 ointments and 1 without any treatment. The ointments were applied twice a day for 10 days. The wound is measured every day until 10 day to calculate the percentage of wound healing. The result is analyzed using ANOVA statistical method. The 20% concentration of banana extract can help reduce blood sugar rate better than the positive control. Therefore, banana corm extract can be considered as potential drug for diabetic.
Keywords: aloxan, banana corm extract, blood sugar rate, rat
Topic: Farmakologi dan Klinik TOOT