Propolis and honey trigona decrease leptin levels of central obesity patients
Rosdiana Natsir, Andi Nilawati Usman, Bau Dilam Ardyansyah, Fendi Fendi
Department of Biochemistry, Medicine Faculty, Hasanuddin University, Indonesia
Department of Midwifery, Medicine Faculty, Hasanuddin University, Indonesia
Research Institution and Community Service, Wuna Agricultural Science University, Indonesia
Abstract
Abstract Objective: This study aimed to examine whether honey and propolis Trigona are able to reduce level of leptin in central obesity human. Methods: It was a quasi-experimental study, population and sample were central obesity and normal weight as control. Sample size was 30 participants taken using purposive sampling. Results: Intervention as long as 14 days make an increased level of leptin as many as 97.076 Pg/ml in control group and decreasing respectively 171.803 Pg/ml and 245.293 Pg/ml in honey and propolis intervention group, both significant statistically. The dose of honey given was 105 mg/days divided into 3 packs, each pack contains 35 mg. The dose of propolis was 60 mg/days and divided into 3 capsules, each of it contains 20 mg. Intervention as long as 14 days and leptin levels examined using human ELISA Kit three times, that is before intervention, 7 days after intervention and 14 days after intervention. Conclusion: Honey and propolis Trigona has the ability to decrease leptin level of central obesity participants. These honey bee products are potential to be a dietary supplement for central obesity patients.
Keywords: Propolis; Honey; Trigona; Leptin
Topic: Herbal medicine