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ICT skills are skills that prospective teachers must possess. Smartphones owned by all prospective teachers allow smartphones to be applied in ICT-based bleended learning. The purpose of this study was to determine the profile of ICT skills of prospective teachers through ICT-based learning on the concept of cell communication. ICT skills using the ETS framework ((Binkey et all, 2012) are measured in two ways, namely observation and self assessment on teacher candidates with the assignment of review articles. The results of the study show that prospective teachers are at the level of mastering independently for all ICT skill indicators, are basic, download, search, navigate, classify, integrate, evaluate, cooperate and create. This study can be concluded that prospective teachers have ICT skills as pedagogical skills.