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As social beings, in every activity communication activities are important things to do. One of the most important communications in human life is health communication. According to the Health Act No.23 of 1992, health is a state of physical, mental and social well-being that allows every person to live productively socially and economically. This health includes 4 aspects, namely physical (body), mental (soul), social, and economic (Notoatmodjo, 2007: 3). The purpose of health communication is as a means of delivering information or messages about health to the community. Health communication is practically useful for health promotion, and preventing disease in a particular area. To achieve goals in health promotion, a strategy is needed before carrying out health promotion. The health promotion strategy consists of advocacy, social support, and also community empowerment. In this case to convey the message of health to the community a promotion mix (marketing mix) is needed so that the message in effective health communication is conveyed to the community as its communicant. In this study the health message in question is related to the dangers of smoking to people in the Non-Smoking Area (KTR). The Special Region of Yogyakarta, which consists of five regency and municipal regions, already has rules regarding the area without cigarettes (KTR). Some of the regencies have KTR rules in the form of regents regulation (Perbup), and the other three regions have rules in the form of Regional Regulations (Perda) KTR. In terms of implementing the policy, it is very important to pay attention to the strategies used and the media that will be used in enforcing the rules in each region. Media communication will be an important factor, especially related to how to design appropriate media and optimize the results of health campaigns in improving the degree of public health.