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In order to achieve a healthy and independent society, it requires involvement of the entire community. Strategy based on togetherness and community empowerment approach by developing preparedness at the village level to accelerate improvement in community health status carried out through Desa Siaga programs. Unfortunately the implementation is constrained in many ways. This study aims to show obstacles and solutions in implementing Desa Siaga. This is a systematic review through journal analysis of Desa Siaga. From the review found 36 related articles. The articles were published between 2010-2018. The results show that barriers in implementing Desa Siaga include human resources, infrastructure, social capital, program sustainability, motivation and joint commitment. The suggested solution is through revitalizing alert villages which involves activities to increase community knowledge, capabilities, and infrastructure facilities. Monitoring and evaluation as well as technological innovations are needed to ensure the sustainability of the program. Strong motivation and joint commitment will be a tremendous support for this program. With the optimization of Desa Siaga, provides a great impact on rural resilience which will ultimately improve the nations health status.