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Biodiesel is a promising alternative fuel to replace petrodiesel. Because biodiesel is renewable, non-toxic, biodegradable, has a low emission profile, and is environmentally friendly. However, the cost of producing biodiesel is higher than petrodiesel. Although biodiesel can be made from various raw materials including vegetable oil, animal fat, and used frying oil, mass production of biodiesel still uses processed vegetable oil. About 60 until 75 percent of the total cost of producing biodiesel comes from raw materials. Therefore, in this study used affordable raw materials, not food and abundant amounts of oil from rice bran. However, rice bran oil has a variety of impurities and the levels are quite high. In this study green solvent is used, namely deep eutectic solvent (DES from ChCl and Ethylene Glycol) and natural deep eutectic solvent (NADES from Betaine Monohydrate and Glycerol) to remove impurities contained in biodiesel from rice bran oil. This study aims to study the comparison of single-stage extraction (single extraction) and multi-stage extraction (multiple extraction) and the effect of stirring speed (laminar until turbulent condition) with DES and NADES solvents on the purity and yield of biodiesel produced. Hence, biodiesel obtained is meets Indonesia national standards (SNI 7182: 2015) with low production costs and is easy to apply on an industrial scale.