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One of the nanoparticles used in the medical world is ZnO nanoparticles. The purpose of this study is to synthesize ZnO nanoparticles using bananas peel extract as a capping agent. This research was conducted in four steps: extraction of three kind of bananas peel (red kapok, ambon, and tanduk), phytochemical test on the bananas peel extract, synthesis of ZnO nanoparticles using the extracts, characterization of ZnO nanoparticles by X-Ray Diffraction (XRD), and the test of the antibacterial activity of ZnO nanoparticles. Based on the phytochemical test it was proven that bananas peel extract contained secondary metabolite such as flavonoids, polyphenols, alkaloids, and saponins in various concentration. From the XRD it can be concluded that ZnO nanoparticles were successfully synthesized. Through the agar diffusion test, it can be showed that ZnO nanoparticles are a promising materials as antibacterial agents. This statement is based on evidence that the diameter of the clear zone produced ranges from 8 to 10 mm.