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Purpose and Background: Drug adherence is a significant problem that induces schizophrenic patients to psychotic relapse. This study aimed to develop an innovation for drug adherence promotion by Kratip Kao. It is a traditional wicker ware made of bamboo for containing sticky rice. But in this study, containing drug instead of sticky rice. Method: The participants consisted of 30 Thai schizophrenic patients, 30 primary caregivers, 30 village heath volunteers. They lived in Yantalad community in Kalasin Province, Northeastern, Thailand. The 15 buddy village health volunteers arranged drugs and took Kratip Kao to schizophrenic patients every day. They also help primary caregivers took drugs to schizophrenic patients. Research tools were questionnaires including continuing home visit report form, satisfaction evaluation form. Data analysis was conducted by using descriptive statistics. Results: The participants were reported satisfication excellent level(100%). In addition, the schizophrenic patients did not re-admit in hospital (100%). Conclusions: Kratip Kao Medication could work for drug adherence promotion among schizophrenic patients. Therefore, psychiatric nurses and health care providers should use this innovation for drug adherence promotion for decreasing psychotic relapse among schizophrenic patients and re-admit rate in hospital.