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Despite the need to assess and treat issues related to patients sexual health, evidence indicates that healthcare professionals still have significant difficulties in doing so. This can have a negative impact on both, quality of care provided and health outcomes. The objective of this study is to identify the attitudes and beliefs of Primary Care Nurses (PCN) towards the management of issues related to patients sexual health. Cross-sectional descriptive methods were used. Data were collected between May 2017 and November 2018 using a self-made anonymous electronic questionnaire. Descriptive univariate and bivariate analysis was performed using Stata14 software. Normal distribution was confirmed using Shapiro Wilk test. T-test, ANOVA and Pearson tests were used for the bivariate analysis. 85 PCN completed the questionnaire (48.5% response rate). Participants were mostly women (84.7%), older than 40 years (mean 45.4; SD 9.2), and experienced (13.8 years; SD 8.0). PMC almost always felt comfortable talking about sex with patients (54.1%), especially with female patients (67.1%), and adolescents (47.1%). Most PCN stated they did not receive proper training at university in terms of sexual health (65.9%). Predominantly, PCN somewhat disagree or totally disagree that sexual health is a priority to discuss with patients (36.5%). PCN believe that always or almost always they do not have time to talk about sex (77.7%). No significant association was found in the bivariate analysis. PCN in Barcelona are keen to talk about sex, however, they believe it is difficult and not a priority. More research is needed to analyze the difficulties mentioned.