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This research was enthused by the use of ICT in Instructional Design. It goes without saying that the use of ICT requires optimal conformation between the ICT features and how Brain Compatible principle processes the information. This study offers a web-based adaptive instructional design model to accommodate personalized ideas in learning. This research and development study was carried out through four stages: synthesizing the conceptual framework of instructional design, analyzing the design and developing initial instructional design application prototype, evaluating the prototype, and revising the BCOOL web-based learning model prototype.This study concludes that the integration of brain compatible learning principles into a BCOOL web-based learning design produced a technology-assisted instructional design model that improve the effectiveness of independent learning. In addition it can be deduced that BCOOL web-based learning model can be used not only for information delivery purposes but also as a cognitive tool for learners.