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This study aims at obtaining students- creative thinking skills in Biology education student. A number of biology education students that take plant microtechnique course at a state university in Sumatera, Indonesia, were involved as participants in this study. Data on creative thinking skills were collected using creative thinking instrument test that have been developed. The data obtained were processed by calculating the percentage (%) for each indicator of creative thinking. Research results show that students- creative thinking on plant microtechnical laboratory practices are: fluency (40.00); flexibility (25.55), originality (26.03), and elaboration (30.00). Based on the results of this study, it is suggested that students- creative thinking skills in plant microtechnical laboratory practices was very low. In order to increase students- creative thinking skills, it is needed revision on instructional strategies for plant microtechnique course.