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This study aims to determine the effect of system quality and quality of information produced by SIMPLE on the level of satisfaction of application users. The population in this study were Government Civil Servants (PNS) in the Sumbawa Regional Secretariat and other Regional Device Organizations. The sample was chosen by purposive sampling technique. The method of data collection is done by questionnaire. The results of multiple linear regression tests obtained a regression quality coefficient of 0.265, while the quality of information is 0.706. The partial test results of each variable obtained a significant value (p) of 0.005 for system quality and 0,000 for the quality of information produced by the system. The value of p <0.05, which means that the quality of the system and the quality of SIMPLE information partially affect to the level of the application user satisfaction. Simultaneous test results (Test F) obtain a significant value (p) of 0,000. Where the value of p <0.05, which means that together the quality of the system and the quality of SIMPLE information affect to the level of application users satisfaction in the Regional Secretariat of Sumbawa Regency.