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Unfavorable sexual behavior in adolescent related and less sexuality knowledge.Objective: To identify the relation between sexuality knowledge with sexual behavior of adolescent. Method : The study type was cross-sectional that using analytic correlation method. The samples in this study were 293 students, they were the adolescents at senior high school 1 Subang. The result was presented in frequency distribution tables, and to identify whether or not the relationship was used chi square statistic. Result : Adolescent mostly had bad sexuality knowledge 64,3%. Most adolescent acquired knowledge of information resources about sexuality from friends 38,6%, and adolescent had a bad sexual behavior 2,7%. There was significant correlation between knowledge of sexuality and adolescent sexual behavior p=0.000 < 0,05. Conclusion :There was significant correlation between knowledge of sexuality with the sexual behavior