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Abstract. Information on the diversity of physico-chemical properties of sweet potato varieties is required to determine their use as raw materials for food, feed, and bioindustry. The purpose of this study was to obtain information on the diversity of physico-chemical characters of sweet potato germplasm accessions using cluster analysis methods. Of the 50 sweet potato accessions that were observed, most of the tubers fleshed were white and cream color, others were purple color, a combination of purple cream, or a combination of orange cream. Of the 11 accessions have high dry matter content (> 30%), 24 accessions are relatively high (> 58.21% db), and 11 accessions are high in reducing sugar (6.83% db). Based on the cluster analysis, 50 sweet potato germplasm accessions are divided into eight groups on the similarity degree of 75%. This information can be used to select the accession of sweet potato as a crossing material in the breeding program the desired high-yield, especially those that are superior in terms of their chemical content for their suitability.