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Bacterial resistance against antibacterial drugs is one of the serious problems in the world of health. However, the rate of increase in bacterial resistance is not matched by the development of new antibacterial drugs. The search for compounds that are potential candidates for antibacterial drugs is important to continue. Oil is an abundant raw material in nature. One plant that contains a lot of oil is candlenut with an oil content of 55-66% of the weight of the seeds. This study aims to determine the antibacterial activity of triglyceride derivatives namely potassium soap, fatty acids, and methyl esters. The stages of research that have been carried out include (1) synthesis, characterization, and identification of potassium soap (2) synthesis, characterization and identification of fatty acids (3) synthesis, characterization, and identification of methyl esters (4 ) Test the antibacterial activity of potassium soap, fatty acid, and methyl ester synthesized against Staphylococcus aureus and Escherichia coli. The results showed that potassium, fatty acid, and methyl ester from candlenut oil were successfully synthesized. These candlenut oil derivatives have antibacterial activity against Staphylococcus aureus and Escherichia coli.