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Co-Cr-Mo alloys is one of the implant materials used to replace bone in humans. This material is widely used because they have excellent in corrosion and wear resistance. In this study, the effect of carbon and nitrogen on microstructure and mechanical properties were investigated. The specimens of Co-Cr-Mo alloy were made by investment casting. The compositions of the alloys are Co-28Cr-6Mo-0.8Si-0.8Mn-0.8Fe-0,2Ni-(0.08-0.25)C-(0-0.2)N. After that process, microstructure of the alloys is characterized by, SEM and XRD testing using bulk and electrolytic extracted specimens. The mechanical properties were determined by tensile and hardness testing. The precipitate content in as-cast alloys was increased with the addition of carbon and nitrogen. The main precipitate formed in the specimens with variations in carbon and nitrogen is M2X type, π-phase, χ-phase, σ-phase, and M2X 6 . In addition, increasing in carbon and nitrogen content in the alloys, increased the value of hardness, ultimate tensile strength, and yield strength in as-cast Co-28Cr-6Mo-0.8Si-0.8Mn-0.8Fe-0.2Ni alloys.