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Antitermite activity methanol extract of lichen Teloschistes flavicnas (SW) Norman was investigated in the laboratory scale. No-choice test was used as method with 5 concentrations tested of 1.25%, 2.5%, 5.0%, 6.25% and 7.5% b/v. The termiticide activity showed that the mortality of termites was increased every day as well as the concentration of the extract increased, at the concentration of 7.5% all termite dead at fourth days. Termiticide activity of methanol extract of T. flavicans was influenced by the GC-MS data that showed 78 chemical components. Vicanicin, methyl oleate, methyl palmitate, and patchouli alcohol was detected as major components that be expected as termiticide. T. flavicans might be possible as a botanical termiticide in the near future.