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Background: Infectious diseases that occur in the community as an immediate case to be taken. Fast and precise handling can be done. This hospital reported 379 cases of infectious diseases in 2016-2017. Variations in infectious diseases transmitted through animals are greater than direct infectious diseases. This study aims to determine the types of diseases transmitted through animals and trends that occur in 2016-2018. Method: This type of research is a quantitative descriptive study with a cross-sectional design. The research sample was all reports of infectious diseases that were published in the Hospital Early Warning System (KDRS). Research location in Type B Government Hospital in Kulon Progo Regency, Yogyakarta. Data collection uses documentation study techniques. Results: There are 11 types of diseases with 8 types of diseases confirmed and 3 diseases that have not been confirmed. Trends in the incidence of infectious diseases transmitted by paralyzed animals. Conclusion: The efforts of hospitals and communities to reduce the incidence are quite successful. A good reporting system is one of the supporting factors for the success of this program. Keywords: Infectious Diseases, Animal Diseases, Trends