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The infiltration of hydrothermal solutions through structures that form veinlets with different alteration levels and variations in physical strength, will influence the consumption of grinding energy during processing operations. This research uses a gold ore vein sample from the Kutawaringin area, Bandung Regency. The sample, analyzed in the field by microscopic analysis, was tested in petrography and mineragraphy in the laboratory, so that it was found to be moderate and low alterated. By taking into account the mineral composition, especially the percent of quartz minerals which when tested for Bond Work Index samples of PO and FR codes require greater energy consumption than those of the GL and KA code samples. This condition has an impact on the selection of the type of grinding equipment, if the alteration of gold ore vein is far more than the low alteration, more feasible choices based on the most vein, so it is more energy efficient. Although it results in decreased grinded production per unit time for low alteration types.