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This study aims to determine the effect of entrepreneurial competence, the use of technology and information on the success of Small and Medium Enterprises (SMEs) in the Globalization era. Also proposed is a framework for entrepreneurial competence. The results showed that entrepreneurial competence, the use of technology and information had a positive effect on the success of SMEs. In the case study there were a number of successful SMEs and most were able to survive and others could not survive due to lack of competence in the field of entrepreneurship. This study seeks to combine several variables, namely entrepreneurial competence, the use of technology and information. The success of SMEs is highly dependent on internal and external factors, including the improvement of financial management supported by theoretical knowledge and the impact of good managerial management.