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Hypertension is a disease that requires long-term treatment, so it takes the regularity of the sufferer in undergoing treatment to control blood pressure and lower the risk of complications. The regularity of drinking hypertension in Puskesmas (Health Center) Ngletih in 2018 was 16% and the irregularities of drinking hypertension amounted to 84%. The purpose of this research is to describe the ownership relationship of JKN and the behavior of smoking with the regularity of taking medication in patients with hypertension. The method used in research is descriptive analytic with cross sectional design. The research population is 661 patients. Large sample of 85 respondents by way of accidental sampling. Data analysis is carried out using the univariate and bivariate analyses (Chi-square). The results of the analysis are the ownership of JKN (P < 0,005; 95% CI = 2.064 – 5.142) and Smoking behavior (p < 0,005; 95% CI = 2.173 – 5.392) related to the regularity of drinking drugs with hypertension in undergoing treatment. Conclusion on this research is the ownership of JKN and smoking behaviour related to the regularity of medication in patients with hypertension in Puskesmas Ngletih Kediri City