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Anthropometry is the most universally applicable, inexpensive, and non-invasive method available to evaluate the proportion, size and composition of the human body. Many research shows that elevated blood pressure and excess weight are established major risk factors for cardiovascular disease (CVD). The preliminary studies addressed issues raised by this relationship. These included the strength of relationship between hypertension and aging, cigarettes smoking, physical activity, the prevalence of hypertension at various levels of obesity, and blood glucose. On the other side, the accuracy of sphygmomanometer is crucial to give the true value of blood pressure. The failure of sphygmomanometer can change blood pressure classification in these patients. In this study, we evaluate the correlation between body weight, aging and blood pressure value as preliminary study to get the critical value of sphygmomanometer calibration. The interactions between blood pressure and body weight and aging were examined using data from 100 participants. Either the systolic and diastolic blood pressure was examined with body weight and age, then the cardiovascular disease (hypertension risk) analyze using WHO classification of blood pressure range. The correlation between blood pressure (both systolic and diastolic) with body weight shows the negative correlation (p<0.05). The odds ratio for hypertension increased by 10% for each additional body weight, compared to 6% for each year increase in age. The correlation between blood pressure with body weight is negative. Furthermore, the association between blood pressure and body weight is higher than age. It is found the new paradigm about critical value of sphygmomanometer calibration, the calibration should have specific range for the certain body weight.