Indonesia Conference Directory

One of reducing the under-five mortality rate strategy caused by Streptococcus pneumonia-like pneumonia is established the strategy of vaccination Pneumococcal Conjugate Vaccine (PCV). This article review aims to examine the impact of implementation PCV-10 or PCV-13 immunization as a national immunization program on the decrease in the incidence of Invasive Pneumococcal Disease (IPD) of children in some countries. The articles search was conducted on PubMed. The research that was included in the review is the research which evaluating the impact of PCV-10 or PCV-13 vaccination on the incidence of IPD (pneumonia, sepsis or meningitis) in children under 5 years; the full text is available, published in 2013-2018 and English version. A total of 114 studies were initially retrieved and reviewed. After further review of references from the retrieved studies, 9 studies were finally selected that met all eligibility criteria. The article was reviewed in nine articles. The study was conducted in Brazil, Finland, and Peru (PCV-10), Italy, Gambia, Denmark, Rwanda, and Canada (PCV-13). Our review study showed that implementation of PCV-10 or PCV-13 in national vaccination program can reduce the incidence of IPD, consist of CAP, meningitis, sepsis, in children who are eligible to be vaccinated in some countries.