Indonesia Conference Directory


<< Back

IN-SILICO ANALYSIS OF KAEMPFEROL AS A COMPETITOR OF ESTROGEN ON ESTROGEN RECEPTOR ALPHA OF ENDOMETRIAL CANCER
Yani Suryani, Opik Taupiqurrohman, Ida Kinasih, Epa Paujiah

Department of Biology
Faculty of Science and Technology
UIN Sunan Gunung Djati
Bandung


Abstract

In-silico study of kaempferol has been performed to determine its potential as a natural estrogen competitor in an effort to suppress the growth of endometrial cancer. This study used a method of molecular decelerating of kaempferol against estrogen receptor alpha, which is compared with natural estrogen in the body. The research process was conducted at the Laboratory of Biology Department of Science and Technology Faculty of UIN Sunan Gunung Djati Bandung, from December 2017 until February 2018. The software used in this study is PyRx-Virtual Screening Tools (for molecular docking process) and Discovery Studio (for pose visualization and data analysis). The results showed that kaempferol is a potential natural estrogen competitor. It is indicated by the lower binding affinity value of kaemperol (-7.0 kcal / mol) than the binding affinity of natural estrogen (-6.7 kcal / mol). The low affinity binding value shows a stable interaction.

Keywords: Binding Affinity, Molecular Deceleration, Kaempferol, Estrogen Receptor Alpha, RMSD

Topic: Computer Science

Link: https://ifory.id/abstract/U8DmYk4EMNKG

Conference: The 4th Annual Applied Science and Engineering Conference (AASEC 2019)

Plain Format | Corresponding Author (Yani Suryani)

Featured Events

<< Swipe >>
<< Swipe >>

Embed Logo

If your conference is listed in our system, please put our logo somewhere in your website. Simply copy-paste the HTML code below to your website (ask your web admin):

<a target="_blank" href="https://ifory.id"><img src="https://ifory.id/ifory.png" title="Ifory - Indonesia Conference Directory" width="150" height="" border="0"></a>

Site Stats