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Particulate Matter 10 micron (PM10) is one of the primary pollutants in the form of dust measuring 10 microns in ambient air. PM10 comes from biogenic and anthropogenic sources. One anthropogenic source that contributes PM10 emissions is industrial activity. The presence of PM10 from industrial activities is not only in terms of concentration but also the heavy metal content of the PM10. Heavy metals have a harmful effect on human health. This study aims to analyze the content of heavy metals in PM10 sourced from industrial activities around the Medan Industrial Area. In addition, this objective also wants to determine the correlation between heavy metal content and industrial activity. Taking PM10 samples using HVAS (High Volume Air Sampler) equipment. Analysis of the content of heavy metals in PM10 was carried out by the ICP-AES (Inductively Couple Plasma Atomic Emission Spectroscopy). The sampling location was in Medan Indutrial Area as many as 3 locations. The results of laboratory tests showed PM10 concentration in front of PT. S was 305.5 micrograms / cubic meter; Mahmud Gang is 66.04 micrograms / cubic meter, and in front of PT. MM is 382 micrograms / cubic meter. Meanwhile, heavy metals content in PM10 was obtained for As of 0.82 - 0.94 micrograms / meter cubic; Cd of 1.42 - 1.62 micrograms / cubic meter; Cr of 0.06 - 0.07 micrograms / cubic meter; Hg of 0.52 - 0.68 micrograms / cubic meter and Pb of 0.29 - 0.33 micrograms / cubic meter Based on the correlation test between pollutant sources and metal content in Medan Industrial Area, the correlation between heavy metals As, Cd, Cr, Hg, and Pb with industry was positively correlated (r = 0.858 - 0.92). this shows that the presence of industry has an effect on heavy metal content in am ambient PM10 at Medan Industrial Area.