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Boron (B) is an important microelement needed in plant growth, to support the production of grain. In an appropriate amount, Boron increases carbohydrate transport and increases enzyme activity. This study aimed to determine the concentration of Boron to obtain the best viability of the seeds of Crassocephalum crepidioides. The research was conducted at the greenhouse, using Random Block Design. The treatment were the concentration level of Boron, consisting of four levels (0%, 50 mg.L-1, 100 mg.L-1 and 150 mg.L-1). All the treatment were replicated three times, and each treatment consisted of 3 samples. The observed variables included total flowers (florets), whole seeds per flower, seed germination (%), germination rates, and growth potential (%). The results showed that the number of flowers and the number of seeds per floret was not significantly different for all treatments tested. The application of 150 mg.L-1 boron produced better seed germination, higher germination rates, and better growth potential compared with the other treatments.