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Education must be able to connect technology advances, the industry and learning in the classroom. These include advances in the fields of chemistry and chemical education to teach students to be able to contribute to solving problems and sustainable development in the future. Chemical education is considered to have a central role in education for sustainable development. For this reason, we need a concept in a chemical education curriculum that can support sustainability. System thinking in chemistry education is relevant to sustainability. Through system thinking, students are challenged to holistically understand the scientific process. This study aims to review the literature on systems thinking and sustainability in chemical education. A total of 9 articles from reputed international journals were the main sources for review. The results of the literature study conducted were the implementation of the system thinking in a chemical education curriculum was a potential thing. The relationship between sustainability and systems thinking were discussed