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Burnout syndrome is an emotional exhaustion syndrome, depersonalization, and reduced personal accomplishment. Nurses working in the emergency department are susceptible to experience burnout due to high work pressure. The objective of this research was to identify the burnout syndrome experienced by nurses working in the emergency department in 5 state hospitals of Bali. This was a descriptive study with cross-sectional approach. Respondents were 141 nurses who works in emergency department of RSUD Wangaya, RSUD Badung, RSUD Sanjiwani, RSUD Tabanan and RSU Bangli. Maslach Burnout Inventory (MBI) was the instrument used to collect the data. The majority of respondents were male (53.9%), age ranged from 26 -35 years. Most nurses working in the emergency department (56%) experienced moderate burnout syndrome. On emotional exhaustion dimension, the majority of nurses experienced moderate burnout 75.2%. Meanwhile, 51.8% and 51.1% of nurses indicated low level of burnout from depersonalization dimension and reduced personal accomplishment dimension, respectively. The hospital management is expected to provide stress management training for nurses with burnout syndrome.