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ABSTRACT Objective The study aimed to analyze relationship between food pattern, mothers- knowledge, family income and nutritional status among children aged 12 to 59 months in Tamalanrea Public Health Center, Makassar City, Indonesia Methods The study used cross sectional study which involved 70 children through purposive sampling method. Food pattern was defined as nutrient intake of energy, carbohydrate, protein and fat. It was collected using food recall 24-hours questionnaire. Mothers- knowledge and family income were collected using developed questionnaire. Children body weight was assessed using standardized and validated weight scale. Nutritional status was defined as body weight for age and categorized based on WHO Anthro plus software. Chi-square test was performed to analyze all variables through SPSS software. Results There were significant relationship between energy, carbohydrate, protein, fat intake and nutritional status among children aged 12 to 59 months (P-value < 0,005). The similar result was showed between mothers- knowledge and nutritional status (P-value < 0,005). In contrast, there were not significant relationship between family income and nutritional status. Conclusion In order to maintain good nutritional status among under-five children, recommended nutrient intake is very important as well as mothers- knowledge in prepare and produce nutritious food for their children.