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The purpose of this study was to identify technological developments in information security systems in hospitals. The method used in this study was a review method with techniques for reviewing and analyzing several papers related to the topic of discussion about the safety of hospital information systems. The results of the study are that the highest threat to the security of hospital information systems is the threat of hackers. The development of technology makes it easy for people, especially in business. In general, this research is in accordance with the expected objectives, namely, to know the security of the health information system network.