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The aim of this paper is development of application learning system for the human body system using webassembly technology to help high school children to recognize system organs of the human body including general functions and diseases in visual learning. Development of system using APPED model which consist of five stages of development. The First stage is analysis and preliminary research stage to analyse the system needs and characteristic, second stage is design system stage to describe the system architecture, flowchart, Screen Design and Storyboard. Third stage is Production stage to develop the system using authoring tool, fourth stage is Evaluation stage to test functionality of system using blackbox testing and test reaction to children using summative evaluation to measure the level of satisfaction program usage. Last stage is dissemination stage to publish applications in general through social media or the internet. The media visual learning system built based on for web applications because it can be used by children anywhere and anytime. The Experimental result it show that applications based on the total score obtained from the questionnaire to 35 respondents obtained a total score of 674 which are based on the attitude categories it show positive attitude the application can help high school children understand the material systems of the human body, with material that has 3D objects, and can recognize the organs of the human body system along with their general functions and diseases and by giving 3D objects as a teaching aid.