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Miura-origami pattern has taken interest of many engineers and mathematicians due to its unique foldability and wide range of engineering applications. However, its mechanical behavior is yet to be fully explored, especially when it is made by additive manufacturing (3D printing) method. In this paper, the compressive behavior of 3D printed lattice structure using the Miura-origami pattern is investigated. Polylactic Acid (PLA) material is used to make the specimen with various printing parameters, i.e infill pattern and density. Moreover, three kind of origami patterns with different folding angle and wall thickness are applied. Finally, the elastic, plastic, and fracture deformation behavior under compressive load is examined. The result is useful to develop a finite element model which can be utilized to comprehensively explore the mechanical behavior under complicated loading condition for various kind of engineering applications.