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This study discusses the process of the SEIRS model on the spread for Hepatitis B. The mathematical model of the SEIRS for Hapatitis B is a model by dividing the population class into four variables namely Susceptible-Exposed-Infected-Recovered-Suspected (SEIRS) which is a four dimensional nonlinear differential equation system. The model obtained analyzed and simulated using data assuming the initial values ​​of variables and parameters and processed using Maple Software. The simulation results provide predictions of the number of Hepatitis B sufferers who can be a preventative solution. If R0>1 , the hepatitis B disease becomes endemic and if R0>=1, the hepatitis B disease will disappear by itself.