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SENECRASSIDIOL, SESQUTERPENOID COMPOUND FROM THE STEMBARK OF Aglaia simplicifolia (Meliaceae)
Nunung Kurniasih(a*), Asep Supriadin(a), Hersa Milawati(b), Rizky Abdulah(c), Desi Harneti(b), Unang Supratman(b,d), Mohamad Nurul Azmi B Mohamad(e)

(a)Department of Chemistry, Faculty of Sciences and Technology, Sunan Gunung Djati Islamic State University, Bandung 40614, Indonesia
(b)Department of Chemistry, Faculty of Mathematics and Natural Sciences,Universitas Padjadjaran, Jatinangor 45363, Indonesia
(c)Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy,Universitas Padjadjaran, Jatinangor 45363, Indonesia
(d)Central Laboratory of Universitas Padjadjaran, Jatinangor 45363, Indonesia
(e)School of Chemical Sciences, Universiti Sains Malaysia,11800 Minden, Penang, Malaysia
* Corresponding author: nunungkurniasih[at]uinsgd.ac.id


Abstract

Previous phytochemical studies from the Aglaia genus reported the presence of terpenoid compound. This research describe the isolation and structure elucidation of sesquiterpend compound from the stembark of Aglaia simplicifolia. Dried stembark of A. simplicifolia extracted with methanol and then partitioned with n-hexane, ethyl acetate, and n-butanol, respectively. The n-hexane extract then was separated and purified with chromatography techniques to obtain isolated compound. The chemical structure of isolated compound were elucidated by IR, NMR 1D, NMR 2D as well as mass spectra and by comparison with those previously reported spectra data. The compound identified as senecrassidiol.

Keywords: Aglaia simplicifolia, stembark, senecrassidiol.

Topic: Chemistry

Link: https://ifory.id/abstract/c2EvpJy6n4Fx

Conference: The 4th Annual Applied Science and Engineering Conference (AASEC 2019)

Plain Format | Corresponding Author (Nunung Kurniasih)

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