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Lettuce is leaf vegetable which consumes as a fresh vegetable. The quality is a crucial role in increasing the market price of lettuce. A large number of nutrient solution is sometimes confusing the farmer or grower which will they choose. The research objectives evaluate five nutrient formulation from local formulator and global formulator.. This reseach conduted in June to July 2018 at Greenhouse of Universitas Padjadjaran, Jatinangor. The experimental design used in this research was completely randomized design with five treatments of nutrient formulation e.g., Sutiyoso (local formulator), Hoagland & Snyder, Hoagland, Shive & Robbins, and Resh Lettuce Anguila. The parameters of lettuce growth (plant height, leaves a number, leaf area, fresh weight of the plant, dry weight of the plant) observe and measure. The data of lettuce plant growth than analyzed with variance analysis &