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Abstract. Dogs bite become a serious problem for the children which require medical attention. Rabies is an infectious disease caused by a virus and attacks the central nervous system of the people. Knowledge and behavior in handling dogs bite should be owned by nursing students such as first aid which can be implemented in the society. The study aims to determine the correlation between knowledge level and behavior of fourth-grade students of ITEKES Bali in handling the first aid of rabies. This research employed analytical correlational design with a cross sectional approach. The population of this research were the fourth grade students of ITEKES Bali. There were 139 respondents selected as the sample by using a stratified random sampling technique. The data were collected by using a self-administered questionnaire to examine the knowledge level and behavior. Among 139 respondents, 92,9% were female. The median age was 22 years old (ranged from 20 to 23 years). Data were analyzed using univariate analysis that showed the knowledge and behavior of fourth-grade students of ITEKES Bali were good. Based on Spearman-s rho test p-value = 0,038 (α<0,05) which mean there was correlation between knowledge level and behavior. This study showed that there is a correlation between knowledge level and behavior of fourth-grade students of ITEKES Bali. Therefore, more knowledge is needed in handling dogs bite as well as good behavior are also needed to treat the patients.