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Enuresis, also known as bed-wetting is a condition where the children at the age of 5 or more urinate on the bed or on their clothes, and it happened often about at least twice a week for 3 months in a row. This research is dedicated to studying the relation between toilet training, physical and family history with the incident of enuresis in children between 5 and 6 years old. A cross-sectional study was conducted in North Denpasar District. The samples were 105 subjects whose study at kindergarten and their parent. Data of the risk factor of enuresis were collected by using questioner and then analyzed by chi-square and Fisher exact test. The result of this research are children who had parents with enuresis history (PR = 3,720), children who had siblings with enuresis history (PR = 4,950), breastfeeding history (PR = 1,920), duration of breastfeeding (PR = 2,133), toilet training (PR = 5,497), and bad physiological history (PR = 1,915) were related to incident of enuresis in children with p-value <0,05. Based on the result, parents, educators, or medical personnel may prevent the incident of enuresis by avoiding the risk factor of enuresis.