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Menstrual discomforts are considered as merely a minor health concern and is given less significance and attention in the public agenda because of the private nature of menstruation. Manufacturers of anion sanitary pads have claimed that anion strips embed on sanitary pads help alleviate menstrual discomforts. Less studies supported this claim, leaving curiosity on how it would affect the health of women. The study evaluated the effectiveness of anion sanitary pads in alleviating menstrual discomforts. Using pre-experimental research design, 30 college students with regular menstruation cycle were purposively selected and given questionnaires before and after anion sanitary pad use. Respondents will rate the level of menstrual discomforts experienced before and after use using a questionnaire. A supply of anion sanitary pads was distributed to the respondents. Wilcoxon signed rank test was used to determine any significant differences in severity of menstrual discomforts before and after anion sanitary pad use. There are no changes in the duration of menses but a marked decrease in the use of anion pads was noted. Menstrual discomforts were still evident before and after anion sanitary pad use but an apparent decline in the level of discomforts was observed. Among the discomforts, irritability, menstrual cramps and mood swings have the highest mean difference. An improvement of the menstrual discomforts in post-assessment was observed. Though hormones estrogen and progesterone were the identified causes of menstrual discomforts, the possibility that serotonin levels may also be a cause of the discomforts was entertained since it also affects mood and physiological changes.