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Abstract- The Industrial Revolution 4.0 greatly affects the activity patterns of human life. Many sectors are feeling the impact of the industrial revolution 4.0, especially industry and education sectors. One of the technologies developed in the era of the Industrial Revolution 4.0, is Cyber Physical Systems (CPS). This technology that integrates communications, control, and physically through the Internet. This paper was prepared aims to determine the model and the application of Cyber Physical Systems in the industry. The method used in the preparation of this paper, by reviewing the literature in journals that are in the range of 2014 - 2019. The search results and study, there are different models and ways of working are applied Cyber Physical Systems industry. Based on the results of the study, it is hoped that alternative CPS models can be applied in the same field or developed in the education sector as learning models.