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Abstract. Complication is an abnormal condition that occurs during the patients undergo hemodialysis. There are common complications occur when the patients undergo hemodialysis such as: muscle cramps, dizziness, headache, arrhythmia, hypotension and hypertension. These complications need to be anticipated, controlled, and overcome to prevent bad condition. The complication can lead to new, more complex problems that can affect the patients, quality of life who undergo hemodialysis therapy, and even cause death. The purpose of this study was to describe the complication that were experienced by hemodialysis patients in the Hemodialysis ward at Tabanan Hospital. This study employed descriptive design with cross-sectional approach. There were 180 respondents recruited as the sample through non-probability sampling with total sampling technique. Data were collected using observation sheet of intradialytic complication and analyzed by using univariate analysis. The data collection was carried out on 1st March-30th April, 2019 in Hemodialysis ward at Tabanan hospital. The findings indicated that there were 98 respondents (54.4%) experienced hypertension as the most common intradialytic complications. There were 75 respondents (41.7%) had less than two intradialytic complications. Intradialytic complications often occurred during the fourth hemodialysis. It can be concluded that the more complications experience by respondents, the higher the chances of patients have a poor quality of life. The intradialytic complications can be reduced, thus the patients quality of life can be improved.