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Hyperuricemia is a condition of elevated blood uric acid level above normal value. One of the risk factors that causes hyperuricemia is high purine intake. This study aimed to assess the relation between purine intake and blood uric acid level in postmenopausal women in the working area of Puskesmas II East Denpasar. Analytic observational method with cross-sectional approach used 100 postmenopausal women collected by simple random sampling technique. Data of daily purine intake from respondents were obtained by semi-quantitative food frequency questionnaires. The study results showed that daily purine intake of respondents was in the range of 142.48-708.47 mg/day and the average was 408.72 ± 153.50 mg/day. Levels of blood uric acid in respondents were in the range of 2.6-8.4 mg/dL and the average was 5.52 ± 1.661 mg/dL. Purine intake had the strongest effect on blood uric acid level (p = 0,019; OR = 3,198; 95% CI = 1,208-8,461) compared with hypertension and BMI (p = 0,040; OR = 2,573 ; 95% CI = 1.043-6.347; p = 0.378; OR = 1.521; 95% CI = 0.598-3.866, respectively). It can be concluded consume high purin diet cause elevated uric acid level among post menopausal women.