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Most of pregnant women had sleep disorders during pregnancy. The factors that can cause sleep disorder are physical and physiological adaptation. This study aimed to identify sleep quality experience by pregnant women and factors associated with it. Cross-sectional study was designed to collect the data from 161 pregnant women who are not having complication during pregnancy and complete the questionnaire. The data were taken by purposive sampling in primary health care Kasihan 1 Tamantirto Bantul Yogyakarta. The data were collected through Pittsburgh sleep quality index (PSQI), Zung-self anxiety rating scale (ZSAS), and numeric rating scale (NRS), then analyzed using Chi square and multiple logistic regressions. The majority of respondent had poor sleep quality (78,9%) and factors that related with sleep quality are anxiety and low back pain. Health care should pay attention to anxiety and low back pain in pregnant women and provide some educations to prevent and treat of anxiety and low back pain during pregnancy