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The purpose of this study was to determine the distribution of yellow mosaic and spotting on California papaya plants in Bengkulu. The research was carried out in January to September 2019 in three districts namely Rejang Lebong, Central Bengkulu, and Seluma districts. The method used in this study is a survey and descriptive method to determine the distribution and incidence of yellow mosaic on papaya plants. Field observations show two types of disease symptoms in papaya tanama. Symptoms of systemic yellow mosaic on papaya leaves, striped mosaic on leaf stalks, ring spot on fruit found in Rejang Lebong Regency. Whereas in Central Bengkulu Regency and Seluma Regency, there were symptoms of brown spots surrounded by yellow halos on the surface of papaya leaves, and small pox spots on papaya fruit. Yellow mosaic disease in several observation locations in Rejang Lebong Regency showed a very high incidence of more than 90% in every land that was observed. While the incidence of brown spot disease in the observation area in Central Bengkulu Regency and Seluma Regency each reached 100%.