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This research aimed to find out the profile of misconception in senior high school students on the concept of acid base strength and the factors caused it. The research design used was qualitative descriptive. The data collection technique was carried out by two tier pictorial multiple choice diagnostic tests on the concept of acid base strength modified by researcher from previous developer, which consist of seven items and had been valid and reliable. In addition, the data was collected by using questionnaire, interview with students identified as having misconceptions and the chemistry teachers who taught the students, and documentation of chemistry textbook. The findings showed that: (1) students were identified as having misconceptions on the concept of acid base strength; (2) the biggest misconception was the target concept of the relationship between acid strength and pH with a percentage of 51.52%; (3) student misconception was caused by various factors, namely the condition of students, experiences, teachers, and textbooks.